English abstract @A Study of Caudal Morphine in Case of Outpatients' Anal Surgery
Tsuneo Araki. Araki Clinic ,Sakai,Osaka.

The purpose of this study is to clarify the effects and side effects of caudal morphine in case of outpatients' anal surgery , and to decide adequate dose of morphine. Two hundred - ninety outpatients were investigated by unique questionnaire for 24 hours after operation from March 1989 through December 1998, which was composed of seven categories,i.e.1)sickness,2)nausea,
3)vomiting,4)analgesia,5)itching, 6)urination, 7)the other troubles. The patients were divided into two groups, one received 2mg dose of morphine hydrochloride (n=64) and the other did 1mg (n=226). About statistics, the results were tested by t-test between two groups at a risk of 5 %. The results were as followed; 1)The average duration of analgesia was 15.2}9.0 hour in 1mg group, beginning time of urination was 9.8}5.6 hour. 2)In the same group, an incidence of headache was 4% , feeling sickness was 15%, nausea was 14% ,vomiting was 4% , itching was 23% and difficulty on urination was 44%. 3)With regard to comparison between two groups, there were significant differences in the average duration of analgesia and the incidence of nausea and vomiting . It was concluded that adequate caudal morphine dose was 1mg (0.02mg/kg body weight)for comfortable analgesia in case of outpatients' anal surgery.

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