Last updated 2005.05.23

1. Koyo Nishida, Chiaki Tonegawa, Toshiyuki Kakutani, Mitsuru Hashida and Hitoshi Sezaki, Statistical moment analysis of hepatobiliary transport of phenol red in the perfused rat liver. Pharmaceutical Research 6: 140-146 (1989)
2. Kimihiko Sato, Kazue Itakura, Koyo Nishida, Yoshinobu Takakura, Mitsuru Hashida and Hitoshi Sezaki, Disposition of a polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate, in the perfused rat liver. Journal of Pharmaceutical Sciences 78: 11-16 (1989)
3. Koyo Nishida, Chiaki Tonegawa, Sachi Nakane, Yoshinobu Takakura, Mitsuru Hashida and Hitoshi Sezaki, Effect of electric charge on the hepatic uptake of macromolecules in the rat liver. International Journal of Pharmaceutics 65: 7-17 (1990)
4. Mitsuru Hashida, Ryo Atsumi, Koyo Nishida, Sachi Nakane, Yoshinobu Takakura and Hitoshi Sezaki, Biliary excretion of mitomycin C dextran conjugates in relation to physicochemical characteristics of carrier dextran. Journal of Pharmacobio-Dynamics 13: 441-447 (1990)
5. Koyo Nishida, Kiyoshi Mihara, Toichi Takino, Sachi Nakane, Yoshinobu Takakura, Mitsuru Hashida and Hitoshi Sezaki, Hepatic disposition characteristics of electrically charged macromolecules in rat in vivo and in the perfused liver. Pharmaceutical Research 8: 437-444 (1991)
6. Koyo Nishida, Yukiko Eguchi, Toichi Takino, Yoshinobu Takakura, Mitsuru Hashida and Hitoshi Sezaki, Hepatic disposition characteristics of ¹¹¹In-labeled lactosaminated bovine serum albumin in rats. Pharmaceutical Research 8: 1253-1257 (1991)
7. Junzo Nakamura, Michihiro Katayama, Mitsuhiko Kido, Koyo Nishida and Hitoshi Sasaki, Decrease of gastrointestinal mucosal damage by salicyluric acid compared with salicylic acid in rabbits. Journal of Pharmacy and Pharmacology 43: 766-773 (1991)
8. Koyo Nishida, Toichi Takino, Yukiko Eguchi, Fumiyoshi Yamashita, Mitsuru Hashida and Hitoshi Sezaki, Pharmacokinetic analysis of uptake process of lactosaminated albumin in rat liver constant infusion experiments. International Journal of Pharmaceutics 80: 101-108 (1992)
9. Junzo Nakamura, Chieko Tagami, Koyo Nishida and Hitoshi Sasaki, Unequal hydrolysis of salicylic acid-D-alanine and salicylic acid-L-alanine conjugate in rabbit intestinal microorganisms. Chemical & Pharmaceutical Bulletin 40: 547-549 (1992)
10. Junzo Nakamura, Michihiro Katayama, Koyo Nishida and Hitoshi Sasaki, An assessment of salicylic acid-induced mucosal damage in vivo by measuring the metabolism of salicylamide in rabbit intestine. Chemical & Pharmaceutical Bulletin 40: 815-818 (1992)
11. Junzo Nakamura, Chieko Tagami, Koyo Nishida and Hitoshi Sasaki, Development of a prodrug of salicylic acid, salicylic acid-L-alanine conjugate, utilizing hydrolysis by rabbit intestinal microorganisms. Journal of Pharmacy and Pharmacology 44: 295-299 (1992)
12. Junzo Nakamura, Michihiro Katayama, Koyo Nishida and Hitoshi Sasaki, An assessment of mucosal damage in vivo: Effect of oral pretreatment with 5-fluorouracil on the intestinal first-pass metabolism of salicylamide in rabbits. Chemical & Pharmaceutical Bulletin 40: 1011-1015 (1992)
13. Junzo Nakamura, Michihiro Katayama, Koyo Nishida and Hitoshi Sasaki, An assessment of indomethacin-induced mucosal damage in vivo by measuring the metabolism of salicylamide in rabbit intestine. Chemical & Pharmaceutical Bulletin 40: 1261-1265 (1992)
14. Junzo Nakamura, Kumiko Asai, Koyo Nishida and Hitoshi Sasaki, A novel prodrug of salicylic acid, salicylic acid-glutamic acid conjugate utilizing Hydrolysis in rabbit intestinal microorganisms. Chemical & Pharmaceutical Bulletin 40: 2164-2168 (1992)
15. Junzo Nakamura, Kumiko Asai, Koyo Nishida and Hitoshi Sasaki, A novel prodrug of salicylic acid, salicylic acid-glycylglycine conjugate, utilizing the hydrolysis in rabbit intestinal microorganisms. Journal of Pharmacy and Pharmacology 44: 713-716 (1992)
16. Junzo Nakamura, Mitsuhiko Kido, Koyo Nishida and Hitoshi Sasaki, Hydrolysis of salicylic acid-tyrosine and salicylic acid-methionine prodrugs in the rabbit. International Journal of Pharmaceutics 87: 59-66 (1992)
17. Junzo Nakamura, Mitsuhiko Kido, Koyo Nishida and Hitoshi Sasaki, Effect of oral pretreatment with antibiotics on the hydrolysis of salicylic acid-tyrosine and salicylic acid-methionine prodrugs in rabbit intestinal microorganisms. Chemical & Pharmaceutical Bulletin 40: 2572-2575 (1992)
18. Kanetoshi Washio, Osami Makaya, Hitoshi Sasaki, Koyo Nishida, Junzo Nakamura and Juichiro Shibasaki, A new aspect of tolbutamide metabolism in the rabbit: the role of 1-butyl-3-(p-formylphenyl)sulphonylurea. Journal of Pharmacy and Pharmacology 45: 231-233 (1993)
19. Hitoshi Sasaki, Yoshiaki Igarashi, Koyo Nishida and Junzo Nakamura, Ocular delivery of the beta-blocker, tilisolol, through the prodrug approach. International Journal of Pharmaceutics 93: 49-60 (1993)
20. Junzo Nakamura, Mitsuhiko Kido, Chieko Tagami, Koyo Nishida and Hitoshi Sasaki, Systemic and presystemic de-conjugation of salicylic acid-arginine conjugate as a prodrug of salicylic acid in rabbits. International Journal of Pharmaceutics 99: 189-195 (1993)
21. Hitoshi Sasaki, Choyu Tei, Koyo Nishida and Junzo Nakamura, Drug release from an ophthalmic insert of a beta-blocker as an ocular drug delivery system. Journal of Controlled Release 27: 127-137 (1993)
22. Koyo Nishida, Mitsuhiko Kido, Hitoshi Sasaki and Junzo Nakamura, Pharmacokinetic analysis of in vivo metabolism of amino acid or dipeptide conjugates of salicylic acid in rabbit intestinal microorganisms. Pharmaceutical Research 11: 160-164 (1994)
23. Hitoshi Sasaki, Yoshiaki Igarashi, Koyo Nishida and Junzo Nakamura, Intestinal permeability of ophthalmic beta-blockers for predicting ocular permeability. Journal of Pharmaceutical Sciences 83: 1335-1338 (1994)
24. Koyo Nishida, Norihito Sato, Hitoshi Sasaki and Junzo Nakamura, Absorption of organic anions as model drugs following application to rat liver surface in-vivo. Journal of Pharmacy and Pharmacology 46: 867-870 (1994)
25. Hitoshi Sasaki, Choyu Tei, Kenzo Yamamura, Koyo Nishida and Junzo Nakamura, Effect of preservatives on systemic delivery of insulin by ocular instillation in rabbits. Journal of Pharmacy and Pharmacology 46: 871-875 (1994)
26. Hitoshi Sasaki, Choyu Tei, Koyo Nishida and Junzo Nakamura, Effect of ophthalmic preservatives on serum concentration and local irritation of ocularly applied insulin. Biological & Pharmaceutical Bulletin 18: 169-171 (1995)
27. Hitoshi Sasaki, Yoshiaki Igarashi, Toshiaki Nagano, Kenzo Yamamura, Koyo Nishida and Junzo Nakamura, Penetration of beta-blockers through ocular membranes in albino rabbits. Journal of Pharmacy and Pharmacology 47: 17-21 (1995)
28. Koyo Nishida, Norihito Sato, Hitoshi Sasaki and Junzo Nakamura, Mechanism for drug absorption from rat-liver surface membrane: Effect of dose and transport inhibitors on the pharmacokinetics of phenol red. Journal of Pharmacy and Pharmacology 47: 227-231 (1995)
29. Hitoshi Sasaki, Kenzo Yamamura, Choyu Tei, Koyo Nishida and Junzo Nakamura, Ocular permeability of FITC-dextran with absorption promoter for ocular delivery of peptide drug. Journal of Drug Targeting 3: 129-135 (1995)
30. Hitoshi Sasaki, Yoshiaki Igarashi, Toshiaki Nagano, Koyo Nishida and Junzo Nakamura, Different effects of absorption promoters on corneal and conjunctival penetration of ophthalmic beta-blockers. Pharmaceutical Research 12: 1146-1150 (1995)
31. Hitoshi Sasaki, Toshiaki Nagano, Kenzo Yamamura, Koyo Nishida and Junzo Nakamura, Ophthalmic preservatives as absorption promoters for ocular drug delivery. Journal of Pharmacy and Pharmacology 47: 703-707 (1995)
32. Koyo Nishida, Norihito Sato, Hitoshi Sasaki and Junzo Nakamura, Effect of albumin on the absorption of phenol red, bromphenol blue and bromosulphonphthalein as model drugs from the liver surface membrane in rats. Biological & Pharmaceutical Bulletin 18: 1548-1550 (1995)
33. Koyo Nishida, Hiroaki Amagishi, Hitoshi Sasaki and Junzo Nakamura, Absorption of phenol red and bromphenol blue as model drugs from the peritoneal cavity around the liver surface in rats. Journal of Pharmacy and Pharmacology 47: 1032-1035 (1995)
34. Hitoshi Sasaki, Masataka Ichikawa, Shigeru Kawakami, Kenzo Yamamura, Koyo Nishida and Junzo Nakamura, In situ ocular absorption of tilisolol through ocular membranes in albino rabbits. Journal of Pharmaceutical Sciences 85: 940-943 (1996)
35. Koyo Nishida, Norihito Sato, Hitoshi Sasaki and Junzo Nakamura, Absorption characteristics of dextrans with different molecular weights from the liver surface membrane in rats: implications for targeting to the liver. Journal of Drug Targeting 4: 141-150 (1996)
36. Hitoshi Sasaki, Masataka Ichikawa, Kenzo Yamamura, Koyo Nishida and Junzo Nakamura, Ocular membrane permeability of hydrophilic drugs for ocular peptide delivery. Journal of Pharmacy and Pharmacology 49: 135-139 (1997)
37. Hitoshi Sasaki, Masataka Ichikawa, Shigeru Kawakami, Kenzo Yamamura, Takahiro Mukai, Koyo Nishida and Junzo Nakamura, In-situ ocular absorption of ophthalmic beta-blockers through ocular membranes in albino rabbits. Journal of Pharmacy and Pharmacology 49: 140-144 (1997)
38. Koyo Nishida, Norihito Sato, Yuki Nakakoga, Takahiro Mukai, Hitoshi Sasaki and Junzo Nakamura: Effect of application volume and area on the absorption of phenol red, as a model drug, from the liver surface in rats. Journal of Pharmacy and Pharmacology 49: 976-980 (1997)
39. Takahiro Mukai, Yasushi Arano, Koyo Nishida, Hitoshi Sasaki, Junzo Nakamura, Hideo Saji and Akira Yokoyama: Pharmacokinetic models to evaluate radiolabeling reagents for protein radiopharmaceuticals. Nuclear Medicine & Biology 25: 31-36 (1998)
40. Takahiro Mukai, Yasushi Arano, Koyo Nishida, Hitoshi Sasaki, Hideo Saji and Junzo Nakamura: In-vivo evaluation of Indium-111-diethylenetriaminepentaacetic acid-labelling for determining the sites and rates of protein catabolism. Journal of Pharmacy and Pharmacology 51: 15-20 (1999)
41. Takahiro Mukai, Yasushi Arano, Koyo Nishida, Hitoshi Sasaki, Hiromichi Akizawa, Kazuma Ogawa, Masahiro Ono, Hideo Saji and Junzo Nakamura: Species difference in radioactivity elimination from liver parenchymal cells after injection of radiolabeled proteins. Nuclear Medicine & Biology 26: 281-289 (1999)
42. Junzo Nakamura, Yayoi Yoshida, Kunihiro Mera, Takahiro Mukai, Koyo Nishida and Hitoshi Sasaki: Continuous microinstillation of phenol red on liver surface for liver site-selective delivery, Biological & Pharmaceutical Bulletin 22: 713-715 (1999)
43. Junzo Nakamura, Atsuko Tsurumaru, Kunihiro Mera, Takahiro Mukai, Koyo Nishida and Hitoshi Sasaki: Absorption of drugs applied to the gastric serosal surface in rats, Pharmacy Pharmacology Communications, 5: 519-522 (1999)
44. Hitoshi Sasaki, Satsuki Kashiwagi, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Masataka Ichikawa: Drug absorption behavior after periocular injections, Biological & Pharmaceutical Bulletin, 22: 956-960 (1999)
45. Hitoshi Sasaki, Satsuki Kashiwagi, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Masataka Ichikawa: Topical delivery system of ophthalmic drugs by periocular injection with viscous solution, Biological & Pharmaceutical Bulletin, 22: 961-965 (1999)
46. Takahiro Mukai, Atsuko Tsurumaru, Kunihiro Mera, Koyo Nishida, Junzo Nakamura, Hitoshi Sasaki and Toshiyuki Sakaeda: Absorption characteristics of model drugs from the gastric serosal surface in rats, Pharmacy Pharmacology Communications, 5: 609-614 (1999)
47. Kenzo Yamamura, Hitoshi Sasaki, Mikiro Nakashima, Masataka Ichikawa, Takahiro Mukai, Koyo Nishida, Junzo Nakamura: Characterization of ocular pharmacokinetics of beta-blockers using a diffusion model after instillation, Pharmaceutical Research, 16: 1596-1601 (1999)
48. Hitoshi Sasaki, Kenzo Yamamura, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Masataka Ichikawa: Characterization of ocular pharmacokinetics of tilisolol after instillation into anesthetized rabbits, Biological & Pharmaceutical Bulletin, 22: 1253-1255 (1999)
49. Koyo Nishida, Yuki Nakakoga, Norihito Sato, Shigeru Kawakami, Takahiro Mukai, Hitoshi Sasaki, Toshiyuki Sakaeda and Junzo Nakamura: Effect of viscous additives on drug absorption from the liver surface in rats using phenol red as a model. European Journal of Pharmaceutics and Biopharmaceutics, 50 (3), 397-402 (2000)
50. Hitoshi Sasaki, Kenzo Yamamura, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Masataka Ichikawa: Pharmacokinetic prediction of the ocular absorption of an instilled drug with ophthalmic viscous vehicle, Biological & Pharmaceutical Bulletin, 23 (11), 1352-1356 (2000)
51. Hitoshi Sasaki, Kenzo Yamamura, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Masataka Ichikawa: Modification of ocular permeability of peptide drugs by absorption promoters, Biological & Pharmaceutical Bulletin, 23 (12), 1524-1527 (2000)
52. Shigeru Kawakami, Kenzo Yamamura, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Toshiyuki Sakaeda, Mikiro Nakashima, Hitoshi Sasaki: Sustained ocular delivery of tilisolol to rabbits after topical administration or intravitreal injection of lipophilic prodrug incorporated in liposomes, Journal of Pharmacy and Pharmacology, 53 (8) Aug, 1157-1161 (2001)
53. Shigeru Kawakami, Koyo Nishida, Takahiro Mukai, Kenzo Yamamura, Junzo Nakamura, Toshiyuki Sakaeda, Mikiro Nakashima and Hitoshi Sasaki: Controlled release and ocular absorption of tilisolol utilizing ophthalmic insert-incorporated lipophilic prodrugs, Journal of Controlled Release, 76 (3) Oct, 255-263 (2001)
54. Koyo Nishida, Yayoi Yoshida, Takahiro Mukai, Shigeru Kawakami, Toshiyuki Sakaeda, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Effect of instillation method on the absorption of phenolsulphonphthalein as a model drug from the liver and small intestinal serosal surface in rats. Journal of Pharmacy and Pharmacology, 53 (10) Oct, 1341-1346 (2001)
55. Shigeru Kawakami, Koyo Nishida, Takahiro Mukai, Kenzo Yamamura, Kazuko Kobayashi, Toshiyuki Sakaeda, Junzo Nakamura, Mikiro Nakashima and Hitoshi Sasaki: Ocular absorption behavior of palmitoyl tilisolol, an amphiphilic prodrug of tilisolol, for ocular drug delivery, Journal of Pharmaceutical Sciences, 90 (12) Dec, 2113-2120 (2001)
56. Shigeru Kawakami, Ryu Hirayama, Keiko Shoji, Rie Kawanami, Koyo Nishida, Mikiro Nakashima, Hitoshi Sasaki, Toshiyuki Sakaeda and Junzo Nakamura: Liver- and lobe-selective gene transfection following the instillation of plasmid DNA to the liver surface in mice, Biochemical and Biophysical Research Communications, 294 (1): 46-50 (2002)
57. Shigeru Kawakami, Tomomi Horimoto, Koyo Nishida, Ryu Hirayama, Takahiro Mukai, Toshiyuki Sakaeda, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Kidney- and site-selective delivery of 5-fluorouracil utilizing the absorption on the kidney surface in rats, Biological & Pharmaceutical Bulletin, 25 (7): 928-930 (2002)
58. Koyo Nishida, Seiichi Nose, Akiko Kuma, Takahiro Mukai, Shigeru Kawakami, Mikiro Nakashima, Hitoshi Sasaki, Toshiyuki Sakaeda and Junzo Nakamura: Absorption characteristics of model compounds with different molecular weights from the serosal caecal surface in rats. Journal of Pharmacy and Pharmacology, 54 (7): 1005-1009 (2002)
59. Shigeru Kawakami, Nao Ohshima, Ryu Hirayama, Masami Hirai, Takashi Kitahara, Toshiyuki Sakaeda, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima and Hitoshi Sasaki: Biodistribution and pharmacokinetics of O-palmitoyl tilisolol, a lipophilic prodrug of tilisolol, after intravenous administration in rats, Biological & Pharmaceutical Bulletin, 25 (8): 1072-1076 (2002)
60. Takahiro Mukai, Kunihiro Mera, Koyo Nishida, Mikiro Nakashima, Hitoshi Sasaki, Toshiyuki Sakaeda and Junzo Nakamura: A novel method for preparation of animal models of liver damage: liver targeting of carbon tetrachloride in rats, Biological & Pharmaceutical Bulletin, 25 (11): 1494-1497 (2002)
61. Ryu Hirayama, Shigeru Kawakami, Koyo Nishida, Mikiro Nakashima, Hitoshi Sasaki, Toshiyuki Sakaeda and Junzo Nakamura: Development of the liver- and lobe-selective nonviral gene transfer following the instillation of naked plasmid DNA using catheter on the liver surface in mice, Pharmaceutical Research, 20 (2): 328-332 (2003)
62. Koyo Nishida, Tominori Honda, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Influence of liver disease on phenolsulfonphthalein absorption from liver surface to examine possibility of direct liver surface application for drug targeting, Biological & Pharmaceutical Bulletin, 26 (7): 988-993 (2003)
63. Junzo Nakamura, Tomomi Horimoto, Ryu Hirayama, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki and Koyo Nishida: Effect of the absorption enhancer saponin on the intrarenal distribution of 5-fluorouracil following its kidney surface application in rats, Biological & Pharmaceutical Bulletin, 26 (7): 1049-1051 (2003)
64. Hitoshi Sasaki, Toshiaki Nagano, Koji Sakanaka, Shigeru Kawakami, Koyo Nishida, Junzo Nakamura, Nobuhiro Ichikawa, Junji Iwashita, Tadahiro Nakamura and Mikiro Nakashima: One-side-coated insert as a unique ophthalmic drug delivery system, Journal of Controlled Release, 92 (3): 241-247 (2003)
65. Junzo Nakamura, Tomomi Horimoto, Ryu Hirayama, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki and Koyo Nishida: Further studies on the kidney- and site-selective delivery of 5-fluorouracil following kidney surface application in rats, Biological & Pharmaceutical Bulletin, 26 (12): 1761-1764 (2003)
66. Takahiro Mukai, Kunihiro Mera, Koyo Nishida, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Pharmacokinetics of phenol red in rat models of liver damage prepared by liver targeting of carbon tetrachloride, Biological & Pharmaceutical Bulletin, 27 (4): 595-597 (2004)
67. Koji Sakanaka, Kouichi Kawazu, Masahide Tomonari, Takashi Kitahara, Mikiro Nakashima, Shigeru Kawakami, Koyo Nishida, Junzo Nakamura and Hitoshi Sasaki: Ocular pharmacokinetic/pharmacodynamic modeling for bunazosin after instillation into rabbits, Pharmaceutical Research, 21 (5): 770-776 (2004)
68. Koyo Nishida, Seiichi Nose, Akiko Kuma, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Absorption of phenolsulfonphthalein as a model across the mesenteric surface in rats to determine the drug absorption route after intraperitoneal administration. Journal of Pharmacy and Pharmacology, 56 (5): 683-687 (2004)
69. Mugen Teshima, Shigeru Kawakami, Koyo Nishida, Junzo Nakamura, Toshiyuki Sakaeda, Hideyuki Terazono, Takashi Kitahara, Mikiro Nakashima and Hitoshi Sasaki: Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach. Journal of Controlled Release, 97 (2), 211-218 (2004)
70. Shigeru Kawakami, Ayaka Harada, Koji Sakanaka, Koyo Nishida, Junzo Nakamura, Toshiyuki Sakaeda, Nobuhiro Ichikawa, Mikiro Nakashima and Hitoshi Sasaki: In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits. International Journal of Pharmaceutics, 278 (2), 255-262 (2004)
71. Ryu Hirayama, Koyo Nishida, Shintaro Fumoto, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Liver site-specific gene transfer following the administration of naked plasmid DNA to the liver surface in mice, Biological & Pharmaceutical Bulletin, 27 (10): 1697-1699 (2004)
72. Hideo Shiota, Mikiro Nakashima, Hideyuki Terazono, Hitoshi Sasaki, Koyo Nishida, Junzo Nakamura, Kotaro Taniyama: Postmortem changes in tissue concentrations of triazolam and diazepam in rats, Legal Medicine, 6 (4): 224-232 (2004)
73. Koyo Nishida, Naoki Tomiyama, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Absorption characteristics of compounds with different molecular weights after application to the unilateral kidney surface in rats. European Journal of Pharmaceutics and Biopharmaceutics, 58 (3), 705-711 (2004)
74. Ryu Hirayama, Koyo Nishida, Shintaro Fumoto, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Unilateral kidney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice, Biological & Pharmaceutical Bulletin, 28 (1): 181-184 (2005)
75. Junzo Nakamura, Kazuko Kobayashi, Shintaro Fumoto, Junya Nishi, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki and Koyo Nishida: Stomach- and site-selective delivery of 5-fluorouracil following its application on the gastric serosal surface in rats, Biological & Pharmaceutical Bulletin, 28 (#): #-# (2005)
76. Koyo Nishida, Rie Fujiwara, Yukinobu Kodama, Shintaro Fumoto, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Regional delivery of model compounds and 5-Fluorouracil to the liver by their application to the liver surface in rats: its implication for clinical use, Pharmaceutical Research, 22 (#): #-# (2005)
77. Koyo Nishida, Akiko Kuma, Shintaro Fumoto, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Absorption characteristics of model compounds from the small intestinal serosal surface and a comparison with other organ surfaces. Journal of Pharmacy and Pharmacology, 57 (#): #-# (2005)
78. Koyo Nishida, Manabu Kamenosono, Akiko Kuma, Shintaro Fumoto, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki and Junzo Nakamura: Delivery advantage to the unilateral kidney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model, Journal of Drug Targeting, 13 (#): #-# (2005)

1. Norihide Higuchi, Yoshio Komine, Tomoyuki Hamamoto, Takashi Kitahara, Rie Kawanami, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Nobuhiro Ichikawa and Hitoshi Sasaki: Investigation of cause of contamination of aseptic total parenteral nutrition (TPN) admixtures, Japanese Journal of Pharmaceutical Health Care and Sciences, 31 (3): 211-216 (2005)

1. Hitoshi Sasaki, Koyo Nishida and Junzo Nakamura: Pyrrolidones as penetration enhancers, in "Percutaneous Penetration Enhancers", Edited by Eric W. Smith and Howard I. Maibach, Chapter 7.1, p211-220, CRC Press (1995)
2. Hitoshi Sasaki, Kenzo Yamamura, Koyo Nishida, Junzo Nakamura and Masataka Ichikawa: Delivery of drugs to the eye by topical application, CHAPTER 11, Progress in Retinal and Eye Research, 15, 583-620 (1996)
3. Hitoshi Sasaki, Kenzo Yamamura, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima and Masataka Ichikawa: Enhancement of ocular drug penetration, Crit Rev Ther Drug Carrier Syst, 85-146 (1999)
4. Shigeru Kawakami, Mitsuru Hashida, Koyo Nishida and Junzo Nakamura: Development of in vivo gene delivery system using cationic liposomes. Drug Delivery System, 15 (2), 89-97 (2000)
5. Shigeru Kawakami, Fumiyoshi Yamashita, Koyo Nishida, Junzo Nakamura and Mitsuru Hashida: Glycosylated cationic liposomes for cell-selective gene delivery, Critical Reviews in Therapeutic Drug Carrier Systems, 19 (2): 171-190 (2002)
6. Koyo Nishida: Development of drug delivery system based on a new administration route for targeting to the specific region in the liver, YAKUGAKU ZASSHI, 123 (8): 681-689 (2003) <Impact Factor: >

1. M. Hashida, K. Nishida, Y. Takakura and H. Sezaki, Hepatic distribution characteristics of macromolecular prodrugs of mitomycin C, The 15th International Symposium on Controlled Release of Bioactive Materials, Basel, Switzerland (1988)
2. K. Nishida, K. Sato, T. Kakutani, Y. Takakura, M. Hashida and H. Sezaki, Statistical moment analysis of hepatobiliary transport of phenol red and macromolecules in the perfused rat liver, The Third International Congress on Mathematical Modeling of Liver Excretory Process, Tokyo, Japan (1990)
3. T. Fujita, Y. Ohtsubo, K. Nishida, M. Hashida and H. Sezaki, Pharmacokinetics of receptor-mediated targeting system with sugar moiety, The 17th International Symposium on Controlled Release of Bioactive Materials, Reno, U.S.A. (1990)
4. M. Hashida, K. Nishida, Y. Takakura and H. Sezaki, Pharmacokinetic evaluation of targeting characteristics of glycosylated and cationized bovine serum albumin, The 18th International Symposium on Controlled Release of Bioactive Materials, Amsterdam, The Netherlands (1991)
5. K. Nishida, H. Sasaki and J. Nakamura, In vivo pharmacokinetic study of salicylic acid-amino acid or dipeptide conjugates in rabbits, The Sixth Japanese-American Conference on Pharmacokinetics and Biopharmaceutics, Buffalo, U.S.A. (1992)
6. H. Sasaki, K. Nishida and J. Nakamura, Modification of ocular and systemic absorption of ocularly applied beta-blocker (tilisolol) by chemical and pharmaceutical approach, The Sixth Japanese-American Conference on Pharmacokinetics and Biopharmaceutics, Buffalo, U.S.A. (1992)
7. K. Nishida, H. Sasaki and J. Nakamura, Drug delivery to the target site in liver by direct application to liver surface, International Symposium Delivery of Protein Drugs-The Next 10 Years, Kyoto, Japan (1993)
8. K. Nishida, H. Sasaki and J. Nakamura, Enhanced absorbability of organic anions as model drugs from peritoneal cavity following intraperitoneal administration to liver surface in rats, The Seventh Japanese-American Conference on Pharmacokinetics and Biopharmaceutics, Hiroshima, Japan (1994)
9. H. Sasaki, T. Nagano, K. Nishida and J. Nakamura, Ocular drug delivery of beta-blocker using one-side coated insert, The Seventh Japanese-American Conference on Pharmacokinetics and Biopharmaceutics, Hiroshima, Japan (1994)
10. K. Nishida, Y. Nakakoga, H. Sasaki and J. Nakamura, Effect of viscosity on the absorption of phenol red as a model drug from the liver surface in rats, The 23th International Symposium on Controlled Release of Bioactive Materials, Kyoto, Japan (1996)
11. K. Yamamura, H. Sasaki, M. Ichikawa, K. Nishida and J. Nakamura, Disposition of drug in precorneal area for ocular delivery, The 23th International Symposium on Controlled Release of Bioactive Materials, Kyoto, Japan (1996)
12. K. Nishida, M. Kamenosono, A. Kuma, S. Kawakami, T. Mukai, H. Sasaki and J. Nakamura, Evaluation of drug targeting ability after application to the organ surface based on a physiological kinetic model. Millennial World Congress of Pharmaceutical Sciences, San Francisco, U.S.A. (2000)
13. T. Horimoto, K. Mera, T. Mukai, K. Nishida, S. Kawakami, J. Nakamura and H. Sasaki, A new method for preparation of hepatic injured animals by utilizing targeting of carbon tetrachloride to the liver. Millennial World Congress of Pharmaceutical Sciences, San Francisco, USA (2000) 
14. R. Fujiwara, S.Kawakami, T. Mukai, K. Nishida, J. Nakamura and H. Sasaki, Possibility of site-selective drug delivery to the liver afterapplication to the liver surface. Millennial World Congress of Pharmaceutical Sciences, San Francisco, U.S.A. (2000)
15. K. Nishida, A. Kuma, Y. Ide, T. Mukai, S. Kawakami, M. Nakashima, H. Sasaki, T. Sakaeda and J. Nakamura: Absoprtion characteristics of drugs from small intestinal serosal surface in rats for prediction of drug disposition after intraperitoneal administration. The 29th International Symposium on Controlled Release of Bioactive Materials. Abstracts p107-108, #60, Seoul, Korea (2002) oral presentation
16. R. Kawanami, T. Kubota, S. Kawakami, K. Nishida, M. Nakashima, H. Sasaki, T. Sakaeda and J. Nakamura: Application of the filter disk on the liver surface for liver site-selective drug delivery in rats. The 29th International Symposium on Controlled Release of Bioactive Materials. Abstracts p715-716, #381. Seoul, Korea (2002) poster presentation
17. M. Teshima, S. Kawakami, K. Nishida, J. Nakamura, T. Sakaeda, T. Kitahara, M. Nakashima, and H. Sasaki: Development of palmitoyl prednisolone, lipophilic prodrug of prednisolone, for liposomal sustained drug release. The 29th International Symposium on Controlled Release of Bioactive Materials. Abstracts p723-724, #385, Seoul, Korea (2002) poster presentation
18. R. Sakamoto, M. Okazaki, K. Nishida, S. Kawakami, M. Nakashima, H. Sasaki, T. Sakaeda and J. Nakamura: Change in the pharmacokinetics of drugs having the different excretion routes during systemic hypothermia in rats. The 29th International Symposium on Controlled Release of Bioactive Materials. Abstracts p764-765, #407, Seoul, Korea (2002) poster presentation
19. Y. Kodama, K. Nishida, M. Shimomura, R. Fujiwara, S. Kawakami, M. Nakashima, H. Sasaki, T. Sakaeda and J. Nakamura: Chemotherapy utilizing absorption from liver surface: possibility of liver site-selective 5-FU delivery in rats. The 29th International Symposium on Controlled Release of Bioactive Materials. Abstracts p766-767, #408, Seoul, Korea (2002) poster presentation
20. T. Kubota, S. Kawakami, K. Nishida, M. Nakashima, H. Sasaki, T. Sakaeda and J. Nakamura: Drug absorption behaviors from the kidney surface and application of the filter disk for kidney site-selective drug delivery in rats. The 29th International Symposium on Controlled Release of Bioactive Materials. Abstracts p772-773, #411, Seoul, Korea (2002) poster presentation
21. K. Shoji, K. Kobayashi, S. Kawakami, K. Nishida, T. Mukai, M. Nakashima, H. Sasaki, T. Sakaeda and J. Nakamura: Gastric site-selective delivery of 5-fluorouracil utilizing the absorption on the gastric serosal surface in rats. The 29th International Symposium on Controlled Release of Bioactive Materials. Abstracts p778-779, #415, Seoul, Korea (2002) poster presentation
22. S. Kawakami, T. Horimoto, T. Mukai, K. Nishida, M. Nakashima, H. Sasaki, T. Sakaeda and J. Nakamura: Kidney site-selective delivery of 5-fluorouracil utilizing the absorption on the kidney surface in rats. The 29th International Symposium on Controlled Release of Bioactive Materials. Abstracts p780-781, #416, Seoul, Korea (2002) poster presentation
23. R. Hirayama, S. Kawakami, K. Nishida, M. Nakashima, H. Sasaki, T. Sakaeda and J. Nakamura: Liver- and lobe-selective gene expression following the administration of naked plasmid DNA to the liver surface in mice. The 29th International Symposium on Controlled Release of Bioactive Materials. Abstracts p782-783, #417, Seoul, Korea (2002) poster presentation
24. ○H. Sasaki, M. Nakashima, M. Tomonari, K. Sakanaka, K. Kawazu, J. Iwashita, J. Nakamura, K. Nishida and S. Kawakami: Ocular pharmacokinetic/pharmacodynamic (PK/PD) modeling for bunazosin after instillation into rabbits, The 62nd Pharmacy and Pharmaceutical Sciences World Congress (FIP 2002), Abstracts p51, PR-P-131, Nice, France (2002)
25. H. Sasaki, M. Nakashima, A. Harada, N. Ichikawa, K. Nishida and J. Nakamura: In vivo gene transfer to the eye utilizing the cationic liposomes after intravitreal injection in rabbits, The 63rd World Congress of Pharmacy and Pharmaceutical Sciences (FIP 2003), Abstracts, p48, DDT-P-001, Sydney, Australia (2003) poster presentation
26. H. Sasaki, K. Sakanaka, K. Kawazu, M. Tomonari, T. Kitahara, M. Nakashima, K. Nishida and J. Nakamura: Ocular pharmacokinetic/pharmacodynamic (PK/PD) modeling for bunazosin after instillation, The 2nd World Congress of the Board of Pharmaceutical Sciences of FIP (PSWC 2004), Abstracts, p.209, Kyoto, Japan (2004).
27. M. Teshima, S. Kawakami, K. Nishida, J. Nakamura, T. Sakaeda, H. Terazono, T. Kitahara, M. Nakashima and H. Sasaki: Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach, The 2nd World Congress of the Board of Pharmaceutical Sciences of FIP (PSWC 2004), Abstracts, p.250, Kyoto, Japan (2004).
28. M. Nakashima, S. Murata, K. Sakanaka, H. Terazono, T. Kitahara, N. Ichikawa, K. Nishida, J. Nakamura, M. Kaibara, K. Taniyama and H. Sasaki: Electrophysiological study for estimation of corneal epithelial disorders after instillation of antiglaucomatous eyedrops, The 2nd World Congress of the Board of Pharmaceutical Sciences of FIP (PSWC 2004), Abstracts, p.394, Kyoto, Japan (2004)
29. H. Sasaki, T. Nakamura, T. Kitahara, H. Terazonno, N. Ichikawa, M. Nakashima, K. Nishida and J. Nakamura: One-side coated insert as a unique ophthalmic drug delivery system, 2004 AAPS Annual Meeting and Exposition, Final Program, p.101 W4242, Baltimore, USA (2004)